INFORM publications
- Guideline development
- Literature review
- Analysis of Joint Registry data
- Qualitative research study
- INFORM randomised controlled trial
- INFORM economic evaluation
Guideline development
- Development of evidence-based guidelines for the treatment and management of periprosthetic hip infection: the INFORM guidelines – Andrew J. Moore | Vikki Wylde |Michael R. Whitehouse | Andrew D. Beswick | Nicola E. Walsh | Catherine Jameson | Ashley W. Blom
Literature review
To assess the existing knowledge about the causes of prosthetic joint infections and the effectiveness of different treatments.
- One- and two-stage surgical revision of peri-prosthetic joint infection of the hip: a pooled individual participant data analysis of 44 cohort studies – Setor K. Kunutsor | Michael R. Whitehouse | Ashley W. Blom | The Global Infection Orthopaedic Management Collaboration
- Re-infection outcomes following one- and two-stage surgical revision of infected hip prosthesis in unselected patients: protocol for a systematic review and an individual participant data meta-analysis (PDF, 632kB) – Setor K Kunutsor | Michael R Whitehouse | Jason Webb | Andrew Toms | Ian Stockley | Adrian Taylor | Stephen Jones | Matthew Wilson | Ben Burston | Tim Board | John-Paul Whittaker | Ashley W Blom | Andrew D Beswick
- Re-Infection Outcomes following One- and Two-Stage Surgical Revision of Infected Hip Prosthesis: A Systematic Review and Meta-Analysis (PDF, 1.5MB) – Setor K. Kunutsor | Michael R. Whitehouse | Ashley W. Blom | Andrew D. Beswick | INFORM Team
- Patient-Related Risk Factors for Periprosthetic Joint Infection after Total Joint Arthroplasty: A Systematic Review and Meta-Analysis (PDF, 762kB) – Setor K. Kunutsor | Michael R. Whitehouse | Ashley W. Blom | Andrew D. Beswick | INFORM Team
- Re-Infection Outcomes Following One- And Two-Stage Surgical Revision of Infected Knee Prosthesis: A Systematic Review and Meta-Analysis (PDF, 1.2MB) – Setor K. Kunutsor | Michael R. Whitehouse | Erik Lenguerrand | Ashley W. Blom | Andrew D. Beswick | INFORM Team
- Health Care Needs and Support for Patients Undergoing Treatment for Prosthetic Joint Infection following Hip or Knee Arthroplasty: A Systematic Review (PDF, 1.1MB) – Setor K. Kunutsor | Andrew D. Beswick | Tim J. Peters | Rachael Gooberman-Hill | Michael R. Whitehouse | Ashley W. Blom | Andrew J. Moore
- Systematic review of risk prediction scores for surgical site infection or periprosthetic joint infection following joint arthroplasty (PDF, 247kB) – Setor K. Kunotsor | Michael R. Whitehouse | Ashley W. Blom | Andrew D. Beswick
- The Alpha-Defensin Immunoassay and Leukocyte Esterase Colorimetric Strip Test for the Diagnosis of Periprosthetic Infection (PDF, 1.1MB) – Michael C. Wyatt | Andrew D. Beswick | Setor K. Kunutsor | Matthew J. Wilson | M.R. Whitehouse | Ashley W. Blom
- Debridement, antibiotics and implant retention for periprosthetic joint infections: A systematic review and meta-analysis of treatment outcomes – Setor K Kunutsor SK | Andrew D. Beswick | Michael R. Whitehouse | Vikki Wylde , Ashley W. Blom
- One- and two-stage surgical revision of infected shoulder prostheses following arthroplasty surgery: A systematic review and meta-analysis – Setor K. Kunutsor | Vikki Wylde | Andrew D. Beswick | Michael R. Whitehouse | Ashley W. Blom
- Implant Fixation and Risk of Prosthetic Joint Infection Following Primary Total Hip Replacement: Meta-Analysis of Observational Cohort and Randomised Intervention Studies – Setor K. Kunutsor | Andrew D. Beswick | Michael R. Whitehouse, Ashley W. Blom, Erik Lenguerrand
- Influence of Fixation Methods on Prosthetic Joint Infection Following Primary Total Knee Replacement: Meta-Analysis of Observational Cohort and Randomised Intervention Studies – Setor K. Kunutsor | Vikki Wylde | Michael Whitehouse, Andrew D Beswick, Erik Lenguerrand, Ashley W. Blom
- One- and two-stage surgical revision of infected elbow prostheses following total joint replacement: a systematic review – Setor K. Kunutsor | Andrew D. Beswick | Michael R. Whitehouse | Ashley W. Blom
Analysis of Joint Registry data
Predictors of prosthetic joint infection and outcomes across different units and surgeons.
- Risk factors associated with revision for prosthetic joint infection after hip replacement: a prospective observational cohort study– Erik Lenguerrand | Michael R. Whitehouse | Andrew D. Beswick | Setor K. Kunutsor | Ben Burston | Martyn L. Porter | Ashley W. Blom
- Description of the rates, trends and surgical burden associated with revision for prosthetic joint infection following primary and revision knee replacements in England and Wales: an analysis of the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man– Erik Lenguerrand | Michael R. Whitehouse | Andrew D. Beswick | Andrew D. Toms | Martyn L. Porter | Ashley W. Blom
- Revision for prosthetic joint infection following hip arthroplasty– Erik Lenguerrand | Michael R. Whitehouse | Andrew D. Beswick | S. A. Jones | Martyn L. Porter | Ashley W. Blom
- Risk factors associated with revision for prosthetic joint infection following knee replacement: an observational cohort study from England and Wales– Erik Lenguerrand | Michael R. Whitehouse| Andrew D. Beswick | Setor K. Kunutsor| Pedro Foguet | Martyn L. Porter| Ashley W. Blom| National Joint Registry for England, Wales, Northern Ireland and the Isle of Man
Qualitative research study
Understanding the treatment of infection after joint replacement, through interviews with patients and surgeons.
- Deep prosthetic joint infection: a qualitative study of the impact on patients and their experiences of revision surgery (PDF, 1.2MB) – Andrew J. Moore | Ashley W. Blom | Michael R. Whitehouse | Rachael Gooberman-Hill
- A UK national survey of care pathways and support offered to patients receiving revision surgery for prosthetic joint infection in the highest volume NHS orthopaedic centres (PDF, 120kB) – Andrew J. Moore | Michael R. Whitehouse | Rachael Gooberman-Hill | Jason Heddington | Andrew D. Beswick | Ashley W. Blom | Tim J. Peters
- Managing uncertainty – a qualitative study of surgeons’ decision-making for one-stage and two-stage revision surgery for prosthetic hip joint infection – Andrew J. Moore | Ashley W. Blom | Michael R. Whitehouse| Rachael Gooberman-Hill
- Infection after knee replacement: a qualitative study of impact of periprosthetic knee infection – Charlotte M. Mallon | Rachael Gooberman-Hill | Andrew J. Moore
- Surgeons are deeply affected when patients are diagnosed with prosthetic joint infection – Charlotte M. Mallon | Rachael Gooberman-Hill | Ashley W. Blom | Michael R. Whitehouse | Andrew J. Moore
- Post-surgery and recovery experiences following one- and two-stage revision for prosthetic joint infection—A qualitative study of patients’ experiences – Cecily K. Palmer | Rachael Gooberman-Hill | Ashley W. Blom | Michael R. Whitehouse | Andrew J. Moore
INFORM randomised controlled trial
Multicenter trial in over 100 patients with prosthetic hip joint infection, to compare patient centered outcomes after 1- and 2-stage surgical revision.
- One-stage or two-stage revision surgery for prosthetic hip joint infection – the INFORM trial: a study protocol for a randomised controlled trialSimon Strange | Michael R. Whitehouse | Andrew D. Beswick | Tim Board | Amanda Burston | Ben Burston | Fran E. Carroll | Paul Dieppe | Kirsty Garfield | Rachael Gooberman-Hill | Stephen Jones | Setor Kunutsor | Athene Lane | Erik Lenguerrand | Alasdair MacGowan | Andrew Moore | Sian Noble | Joanne Simon | Ian Stockley | Adrian H. Taylor | Andrew Toms | Jason Webb | John-Paul Whittaker | Matthew Wilson | Vikki Wylde | Ashley W. Blom
- Clinical and cost effectiveness of single stage compared with two stage revision for hip prosthetic joint infection (INFORM): pragmatic, parallel group, open label, randomised controlled trialAshley W. Blom | Erik Lenguerrand | Simon Strange | Sian Noble | Andrew D. Beswick | Amanda Burston | Kirsty Garfield | Rachael Gooberman-Hill | Shaun Harris | Setor Kunutsor | Athene Lane | Alasdair MacGowan | Sanchit Mehendale | Andrew Moore | Ola Rolfson | Jason Webb | Matthew Wilson | Michael R. Whitehouse
- Infection after total joint replacement of the hip and knee: research programme including the INFORM RCT Ashley W. Blom | Andrew D. Beswick | Amanda Burston | Fran E. Carroll | Kirsty Garfield | Rachael Gooberman-Hill | Shaun Harris | Setor Kunutsor | Athene Lane | Erik Lenguerrand | Alasdair MacGowan | Charlotte Mallon | Andrew Moore | Sian Noble | Cecily K. Palmer | Ola Rolfson | Simon Strange | Michael R. Whitehouse
- What are patients’ preferences for revision surgery after periprosthetic joint infection? A discrete choice experiment Fran Carroll | Rachael Gooberman-Hill | Simon Strange | Ashley W. Blom | Andrew Moore
INFORM economic evaluation
To assess the value for money of treatments.
- Clinical and cost effectiveness of single stage compared with two stage revision for hip prosthetic joint infection (INFORM): pragmatic, parallel group, open label, randomised controlled trial Ashley W. Blom | Erik Lenguerrand | Simon Strange | Sian Noble |Andrew D. Beswick | Amanda Burston | Kirsty Garfield | Rachael Gooberman-Hill | Shaun Harris | Setor Kunutsor | Athene Lane | Alasdair MacGowan | Sanchit Mehendale | Andrew Moore | Ola Rolfson | Jason Webb | Michael Wilson | Michael R. Whitehouse